Addressing Drug Resistance: How New Molecular Targets are being Explored to Overcome Refractory Herpes Simplex Virus Strains.
While the existing nucleoside analogs are effective for the vast majority of patients with Herpes Simplex Virus (HSV), the emergence of **drug-resistant strains** presents a critical clinical challenge, particularly in immunocompromised patient populations, such as those with advanced HIV or undergoing chemotherapy. These resistant strains, often stemming from mutations in the viral enzyme...
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