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Shubhangi Fusam added blog Health
2025-11-18 11:19:41 -

Short-Read Titans vs. Long-Read Innovators: Analyzing the Fierce Competitive Landscape in the Next Generation Sequencing Market and Emerging Technologies.
The history of genomics is essentially a history of exponential cost reduction, and Next Generation Sequencing (NGS) is the primary driver of this trend. The cost of sequencing a human genome has plummeted from billions of dollars two decades ago to under a thousand dollars today, a rate of decrease far outpacing Moore’s Law. This profound affordability has been the single most critical...

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Pratiksha Dhote added blog Health
2025-11-20 11:26:32 -

Beyond Human DNA: Analyzing the Critical Role of Next Generation Sequencing in Metagenomics, Agriculture, and Infectious Disease Surveillance
A major advancement within the Next Generation Sequencing (NGS) domain is the emergence of **single-cell sequencing (SCS)**. Traditional bulk sequencing methods analyze DNA or RNA from thousands of cells, providing an average genomic profile that often obscures critical biological differences between individual cells. SCS overcomes this limitation by isolating and sequencing the...

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Pratiksha Dhote added blog Health
2025-11-21 06:49:20 -

The Emerging Utility of Long-Read Sequencing: How Third-Generation Technologies are Resolving Complex Genomic Regions and Structural Variants.
One of the most successful commercial applications of **Next Generation Sequencing (NGS)** is **Non-Invasive Prenatal Testing (NIPT)**. NIPT screens for common chromosomal abnormalities, such as Down syndrome (Trisomy 21), using only a small sample of maternal blood. The test works by sequencing cell-free DNA (cfDNA) circulating in the mother's plasma, which contains a fraction of DNA shed by...

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